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Tyrosine hydroxylase (prelimbic cortex only) and choline acetyltransferase immunoreactivity levels were decreased in adolescent intermittent ethanol-exposed rats compared with controls.

Risky choice was negatively correlated with choline acetyltransferase, implicating decreased forebrain cholinergic activity in risky choice.

A significant unmet need in treating neurodegenerative disease is effective methods for delivery of biologic drugs, such as peptides, proteins, or nucleic acids into the central nervous system (CNS).

Acute ethanol had no effect on risky choice in either group of rats.Sea salt, rock salt or table salt is there a difference & which is better?Sea salt, rock salt and table salt all contain around 100% sodium chloride which means that too much of any of them will have a negative effect on your health.Using an in vivo phage-display screen, we identify a peptide, targeted axonal import (TAx I), that enriched recombinant bacteriophage accumulation and delivered protein cargo into spinal cord motor neurons after intramuscular injection.In animals with transected peripheral nerve roots, TAx I delivery into motor neurons after peripheral administration was inhibited, suggesting a retrograde axonal transport mechanism for delivery into the CNS.It is argued that sea salt contains more minerals than table salt so is better for your health.